GEORGE, Y. DANILOFF,LOUIS, C. SEHL,OLOF, MIKAEL TROLLSAS,JACQUELINE SCHROEDER,DAVID, M. GRAVETT,PHILIP, M. TOLEIKIS
申请号:
HK15105201.7
公开号:
HK1204584A
申请日:
2015.06.01
申请国别(地区):
HK
年份:
2015
代理人:
摘要:
Crosslinkable compositions are provided that readily crosslinkin situ to provide crosslinked biomaterials. The composition contains at least two biocompatible, non-immunogenic components having reactive groups thereon, with the functional groups selected so as to enable inter-reaction between the components, i.e., crosslinking. In one embodiment, a first component has nucleophilic groups and a second component has electrophilic groups. Additional components may have nucleophilic or electrophilic groups. Methods for preparing and using the compositions are also provided as are kits for delivery of the compositions. Exemplary uses for the crosslinked compositions include tissue augmentation, biologically active agent delivery, bioadhesion, and prevention of adhesions following surgery or injury.