PASTOR FERNÁNDEZ JOAQUÍN,RAMOS LIMA FRANCISCO JAVIER,HERNÁNDEZ HIGUERAS ANA ISABEL,MARTÍNEZ GONZÁLEZ SONIA,MARTÍN HERNANDO José Ignacio,SALUSTE CARL GUSTAVE PIERRE,GONZÁLEZ CANTALAPIEDRA Esther,BLANCO
申请号:
IN5817/DELNP/2012
公开号:
IN2012DN05817A
申请日:
2012.06.29
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
There is provided compounds of formula (I) wherein R R R and R have meanings given in the description (and which compounds are optionally substituted as indicated in the description) and pharmaceuticaly acceptable esters amides solvates or salts thereof which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PIM family kinase such as PIM 1 PlM 2 and/or PIM 3) is desired and/or required and particularly in the treatment of cancer or a proliferative disease. There is also provided combinations comprising the compounds of formula (I).