ROTHER, RUSSELL P.,BEDROSIAN, CAMILLE,SQUINTO, STEPHEN P.,BELL, LEONARD
申请号:
CA2742802
公开号:
CA2742802C
申请日:
2009.11.10
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present disclosure relates to, inter alia, compositions containing aninhibitor of human complement and use ofthe compositions in methods for treating or preventing complement-associateddisorders. In some embodiments, the inhibitor ischronically administered to patients. In some embodiments, the inhibitor isadministered to a patient in an amount and with afre-quency to maintain systemic complement inhibition and preventbreakthrough. In some embodiments, the compositions contain anantibody, or antigen-binding fragment thereof, that binds to a humancomplement component C5 protein or a fragment of theprotein such as C5a or C5b.