Phamaceutically acceptable salts o f pyrrolo-nitrogenous heterocyclic derivatives, preparation method and medical use thereof are disclosed. More specifically, phamaceutically acceptable salts o f ( R,Z)-2-(5-fluoro-2-oxo-l,2-dihydro-indol-3- methylene ) -5 -( 2-hydroxy - 3-moIpholinyl -4-yl-propyl ) -3-methyl - 5,6 ,7 ,8 -tetrahydro - l H-p o l o [ 3 ,2-c]azepin -4-one represented b y formula (I), the preparation method and the use thereof as therapeutic agents, especially as protein kinase inhibitors, are disclosed.