GOTCHEV, DIMITAR B.,DORSEY, BRUCE D.,KAKARLA, RAMESH,BI, YINGZHI,NGUYEN, DUYAN,CHEN, SHUAI,WOOD, MARK CHRISTOPHER,BAILEY, LAUREN DANIELLE,HOLLAND, RICHARD JAMES
申请号:
CA3040919
公开号:
CA3040919A1
申请日:
2017.11.03
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention includes substituted pyridinone-containing tricyclic compounds, and compositions comprising the same, that can be used to treat or prevent hepatitis B virus (HBV) infection in a patient. In certain embodiments, the compounds and compositions of the invention inhibit and/or reduce HBsAg secretion.