Substituted annulated pyrimidines and triazines, and use thereof

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专利权人:

BAYER INTELLECTUAL PROPERTY GMBH;BAYER PHARMA AKTIENGESELLSCHAFT

发明人:

GRIEBENOW NILS,WUNDER FRANK,FOLLMANN MARKUS,HÜBSCH WALTER,VAKALOPOULOS ALEXANDROS,TERSTEEGEN ADRIAN,LANG DIETER,REDLICH GORDEN,STASCH JOHANNES-PETER

申请号：

NZ62639413

公开号：

NZ626394A

申请日:

2013.01.10

申请国别(地区):

NZ

年份:

2016

代理人:

摘要：

Disclosed are substituted annulated pyrimidines and triazine compounds of formula (I), wherein the substituents are as define in the specification. The compounds are useful for the treatment and/or prophylaxis of cardiovascular diseases. Examples of a compound of formula (I) are: 2-[1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-4-(3-hydroxypropyl)-5,5-dimethyl-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one 4-(Aminomethyl)-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-5,5-dimethyl-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one acetate

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中国工程科技知识中心

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