Champion Brian Robert,Pierce Brian Gregory,Contillo Jr. Leonard Gabriel,Hawkins Julie Jia Li,Merson James Richard,Qiu Xiayang,Wyatt David Michael,Fraser James Downey,Eisenbraun Michael Dale,Ullah Jaki
申请号:
NZ71062610
公开号:
NZ710626A
申请日:
2010.08.23
申请国别(地区):
NZ
年份:
2017
代理人:
摘要:
Discloses a composition comprising a first immunogen and a second immunogen, wherein each of the first and second immunogens comprises at least one antigenic proprotein convertase subtilisin-kexin type 9 (PCSK9) peptide linked to an immunogenic carrier, wherein the antigenic PCSK9 peptide of the first immunogen consists of an amino acid sequence selected from the group consisting of SEQ ID NOs: 182-188, 317, 401, 402, and 403, and wherein the antigenic PCSK9 peptide of the second immunogen consists of an amino acid sequence selected from the group consisting of SEQ ID Nos: 46-101, 314, 318, and 319, wherein the sequences are as defined in the complete specification.