A medical device assembly is disclosed, comprising: a medical device a fluid and a package forming a storage compartment, which at least partly accommodates the medical device, and a fluid compartment, housing the fluid, wherein a first joint separates the storage compartment and the fluid compartment, the first joint forming a first rupture zone. An additional outer layer is arranged over the fluid compartment, wherein the additional outer layer is joined to the package by a second joint, and at least part of the second joint forms a second rupture zone. The strength and/or location of the second rupture zone is adapted to ensure that compression of the fluid within the sealed and closed internal cavity for release of said fluid results in opening of said first rupture zone in a state where the package at and in the vicinity of the first rupture zone is unconnected to the additional outer layer. This can be e.g. be achieved by the strength of the second rupture zone being lower than the strength of the first rupture zone, whereby compression of the fluid within the sealed and closed internal cavity for release of said fluid results in a rupture at the second rupture zone prior to rupture at the first rupture zone. Additionally or alternatively, the second rupture zone may be separated from the fluid compartment and the first rupture zone in a longitudinal direction of the assembly.