The disease condition determination device according to the present invention is provided with: a first separation degree calculation unit for calculating a degree of separation on the basis of first load blood flow information which is blood flow information for a task state in which a first load for varying the blood flow state of a subject is imposed on the subject, and second load blood flow information which is blood flow information for a control state in which a second load different from the first load is imposed on the subject, from among blood flow information obtained by measuring blood flow in the brain of a subject by optical measurement using near-infrared rays an oscillation detection unit for detecting oscillation in variation of the hemoglobin concentration of the blood flow of the subject on the basis of non-load blood flow information a phase detection unit for detecting the phase of the variation in hemoglobin concentration of the blood flow of the subject on the basis of the non-load blood flow information and a determination unit for determining the disease condition of the subject on the basis of the degree of separation calculated by the first separation degree calculation unit, the oscillation detected by the oscillation detection unit, and the phase detected by the phase detection unit.Linvention concerne un dispositif de détermination détat de maladie, comprenant : une première unité de calcul de degré de séparation pour calculer un degré de séparation sur la base des premières informations de flux sanguin de charge qui sont des informations de flux sanguin pour un état de tâche dans lequel une première charge pour faire varier létat de flux sanguin dun sujet est imposée sur le sujet, et des secondes informations de flux sanguin de charge qui sont des informations de flux sanguin pour un état contrôle dans lequel une seconde charge différente de la première charge est imposée sur le sujet, parmi les informations de flux sanguin obtenues en
