Disclosed is an anti-eccentric load and anti-winding device for pulsator washing machines with different blades and barrel diameters. In the device, a hollow separator fixing column (5) is closed at the bottom thereof, and provided with four space separators (1) evenly arranged along a circumferential direction thereof. The lower edges of the space separators (1) are curved so as to match a curve at the outer side of the bottom of a washing barrel, and a water guide hole (2) is formed in each space separator (1). A grip (3) is disposed at the upper end of the hollow separator fixing column (5). A water injection port (4) communicating with an inner cavity of the hollow separator fixing column (5) is disposed at the center of the grip (3), and a water injection port closing bolt (13) is disposed on the water injection port (4). The anti-eccentric load and anti-winding device can prevent deformation or even damage caused by excessive winding of clothing and reduce eccentric loads of pulsator washing machines in