BRUSH POLYMER-ASSISTED COMPACTION OF OLIGONUCLEOTIDES

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专利权人:

NORTHEASTERN UNIVERSITY

发明人:

Ke ZHANG,Xueguang LU

申请号：

US15750360

公开号：

US20180230467A1

申请日:

2016.08.04

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The disclosed subject matter relates to brush polymer-oligonucleotide conjugates comprising oligonucleotides covalently attached to the backbone of a non-cationic, sterically congested brush polymer and the use of such polymer-oligonucleotide conjugates in antisense gene regulation and as diagnostic agents.

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