STACH JAN,KRULIS RADIM,CERNY JOSEF,RIDVAN LUDEK,DAMMER ONDREJ,KREJCIK LUKAS,RADL STANISLAV
申请号：
IN1099/KOLNP/2015
公开号：
IN2015KN01099A
申请日:
2015.04.21
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
A method of preparing the potassium salt of azilsartan medoxomil of formula I, in which a solvate of azilsartan medoxomil of formula II with a solvent selected from the group that consists of dimethyl acetamide or N-methyl pyrrolidone or their mixtures with other solvents is prepared, or re-crystallized from dimethyl acetamide or N-methyl pyrrolidine or their mixtures with other solvents, and, in the next step, converted to the potassium salt using a potassium source in a suitable solvent.
