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METAL-POLYSACCHARIDE CONJUGATES: COMPOSITIONS AND SYNTHESIS
专利权人:
TAIWAN HOPAX CHEMS. MFG. CO.; LTD
发明人:
WEI, I-CHIEN,YANG, DAVID J.,YU, DONG-FANG
申请号:
CA2633526
公开号:
CA2633526C
申请日:
2008.06.02
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The current disclosure, in one embodiment, includes a polysaccharide conjugate. This conjugate has a polysaccharide and at least one monomeric amino acid having an O-group covalently bound to the polysaccharide. The conjugate also has at least one metal conjugated by the O-group of the amino acid. According to another embodiment, the disclosure provides a method of synthesizing a polysaccharide conjugate by covalently bonding a monomeric amino acid having an O-group to a polysaccharide and by conjugating a metal to the O-group to form a polysaccharide conjugate. According to a third embodiment, the disclosure relates to a method of killing a cancer cell by administering to the cell an effective amount of a polysaccharide conjugate. This conjugate has a polysaccharide and at least one monomeric amino acid having an O-group covalently bound to the polysaccharide. The conjugate also has at least one metal conjugated by the O-group of the amino acid.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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