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NOVEL CHIMERA GENE ATF7IP-PDGFRB FOR ACUTE LYMPHOBLASTIC LEUKEMIA
专利权人:
发明人:
申请号:
EP14863814.1
公开号:
EP3072964A1
申请日:
2014.11.17
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
To identify a mutation that can serve as an indicator for predicting the effectiveness of drug treatment in cancers such as leukemia to provide a means for detecting said mutation and to provide a means for identifying, based on said mutation, patients with cancer or subjects with a risk of cancer, in whom a drug targeting a gene having said mutation or a protein encoded by said gene shows a therapeutic effect.A method for detecting a gene fusion serving as a responsible mutation (driver mutation) for cancer, the method comprising the step of detecting an ATF7IP-PDGFRB fusion polynucleotide or a polypeptide encoded thereby, in an isolated sample from a subject.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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