BAUER, CHRISTOPHER TODD,BOURNER, MAUREEN JERI,BOYLE, MELANIE,CASPERSON, GERALD FRIES,GRIGGS, DAVID WILLIAM,HEAD, RICHARD DAVID,JOY, WILLIAM DEAN,MAZZARELLA, RICHARD ALLEN,MINTER, RALPH RAYMOND,MOFFAT,
申请号:
CA2604357
公开号:
CA2604357C
申请日:
2006.04.13
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention relates to antibodies including human antibodies andantigen- binding portions thereof that bind to P-cadherin, and that functionto inhibit P-cadherin. The invention also relates to heavy and light chainimmunoglobulins derived from human P- cadherin antibodies and nucleic acidmolecules encoding such immunoglobulins. The present invention also relates tomethods of making human P-cadherin antibodies, compositions comprising theseantibodies and methods of using the antibodies and compositions. The inventionalso relates to transgenic animals or plants comprising nucleic acid moleculesof the present invention.