COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
发明人:
WALKER, ANDREW ALLAN,WEISMAN, SARAH,SUTHERLAND, TARA
申请号：
CA2904749
公开号：
CA2904749A1
申请日:
2013.03.26
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present disclosure provides polypeptides which encode a silk polypeptide, wherein at least a portion of the polypeptide has a coiled coil structure comprising at least 10 copies of the heptad sequence abcdefg, and wherein at least 25% of the amino acids at position a are alanine residues and at least 20% of the amino acids at position d are aromatic residues. The present disclosure also provides nucleic acids encoding such polypeptides, and recombinant cells and/or organisms which synthesize the polypeptides. The polypeptides can be used for a variety of purposes such as in the production of personal care products, plastics, textiles, and biomedical products.
