Peptides related to certain portions of the arginine deiminase enzyme from the bacterium Streptococcus cristatus are provided that disrupt the formation and composition of biofilms containing the oral pathogen Porphyromonas gingivalis, and also modulate the virulence of P. gingivalis. Pharmaceutical compositions containing such peptides and method of using the same are disclosed.L'invention concerne des peptides associés à certaines parties de l'enzyme arginine déiminase de la bactérie Streptococcus cristatus qui perturbent la formation et la composition de biofilms contenant le pathogène oral Porphyromonas gingivalis , et modulent également la virulence de P. gingivalis.L'invention concerne des compositions pharmaceutiques contenant de tels peptides et leur procédé d'utilisation.
