Philip J. BIRBARA,Jeffrey S. CUMMINGS,Karl GINTER,Krishna RAMAN
申请号：
US15265584
公开号：
US20170071840A1
申请日:
2016.09.14
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Microemulsions and soluble alkali metal salts of relatively insoluble aglycone polyphenols within oral hygienic products are disclosed for treating oral inflammatory disorders. The formulations can act as a bactericide or bacteriostat. The methods include the process associated with the formation of a high temperature polyphenol/surfactant concentrate, a nano-particulate precipitation process in the presence of a surfactant and the solubilization of relatively insoluble aglycone polyphenols/flavonoids by the formation of soluble alkali metal salts within alkaline oral compositions. Also disclosed are compositions that persist in the oral cavity, penetrate teeth, and facilitate or enhance the delivery of chemical elements and active ingredients to teeth for preventing or treating disorders and diseases of the oral cavity. Methods of use, and methods of making, the aforementioned compositions are also disclosed.
