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Fusion protein SAmB, coding gene and application thereof
专利权人:
PR China;Institute of Microbiology and Epidemiology; Academy of Military Medical Sciences
发明人:
Wang, Hui,Cai, Kun,Li, Tao,Hou, Xiaojun,Wang, Qin,Gao, Xiang
申请号:
AU2011304942
公开号:
AU2011304942A1
申请日:
2011.09.09
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Disclosed are a fusion protein SAmB, a coding gene and an application thereof. The fusion protein provided in the present invention is named SAmB, comprising on the N-terminal a Shiga toxin type-II A subunit mutant protein, and on the C-terminal a Shiga toxin type-I B subunit protein. The Shiga toxin type-II A subunit mutant protein is prepared by mutating the active site amino acid residues of a Shiga toxin type-II A subunit protein. The fusion protein SAmB of the present invention can be used to prepare a medicament for use in the prevention and/or treatment of a Shiga toxin pathogenic bacteria infection or a complication of the infection.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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