PROBLEM TO BE SOLVED: To provide a method of treating a transient impairment of the motility of the gastrointestinal system resulting from gastroesophageal reflux disease, ileus (intestinal or bowel obstruction), emesis, gastroparesis, irritable bowel syndrome, constipation or colonic pseudo-obstruction, in particular from postoperative ileus.SOLUTION: The present invention relates to a method of treating a transient impairment, in which the gastrointestinal motility is stimulated by administering to a patient a therapeutically effective amount of a peptidyl analog which holds ghrelinergic activation selected from H-Inp-D-2-Nal-D-Trp-Phe-Apc-NH, H-Inp-D-Bal-D-Trp-Taz-Apc-NH, H-Inp-D-Bal-D-Trp-2-Thi-Apc-NH, and (Aib,Glu(NH-hexyl))hGhrelin(1-28)-NH.SELECTED DRAWING: None【課題】胃食道逆流症、イレウス（腸又は腸管閉塞）、嘔吐、胃麻痺、過敏性腸症候群、便秘、又は結腸の偽閉塞、中でも術後イレウスより生じる胃腸系の運動の一過性障害を治療する方法の提供。【解決手段】H-Inp-D-2-Nal-D-Trp-Phe-Apc-NH2、H-Inp-D-Bal-D-Trp-Taz-Apc-NH2、H-Inp-D-Bal-D-Trp-2-Thi-Apc-NH2、および(Aib2,Glu3(NH-ヘキシル))hGhrelin(1-28)-NH2、より選ばれる作動性グレリン活性を保有するペプチジル類似体の治療有効量を患者へ投与することにより胃腸系の運動を刺激する一過性障害害の治療方法。【選択図】なし
