An optical device, generally a camera head connected to an endoscope, provides multiple modes of operation, producing images with varying depth of field and/or resolution characteristics. Light from the endoscope passes through a variable aperture and a beam splitter and is directed to two or more independent image sensors. The image sensors may be moved, relative to each other, along their optical paths. An image processor combines the collected images into a resultant image. Adjustment of the relative positions of the image sensor and/or the diameter of the variable aperture permits the selection of optical properties desired, with a larger depth of field, and/or higher resolution than possible with a conventional system. Images may be collected through multiple acquisition periods, and a further enhanced image may be generated therefrom. The camera head may automatically make adjustments based on identifiers of the optical configuration of the attached endoscope.
