ПРАДОС ОСУНА Хосе (ES),ГАРСИЯ-ГРАНАДОС ЛОПЕС ДЕ ИЕРРО, Андрес (ES),ПАРРА САНЧЕС Андрес (ES),АРТИНЕС РОДРИГЕС Антонио (ES)
申请号:
RU2010135252/15
公开号:
RU2010135252A
申请日:
2009.04.03
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. The use of olivic acid or any of its derivatives in the manufacture of a medicament for the treatment of pathologies including activation of cyclooxygenase-2 (COX-2). ! 2. The use of olivic acid or any of its derivatives in the manufacture of a medicament for the regeneration of chondrocytes in tissues. ! 3. The use of olivic acid or any of its derivatives according to any one of claims 1 or 2 in the manufacture of a medicament for the treatment of pathologies selected from the list including: arthrosis, rheumatoid arthritis, sciatica, fibromyalgia, patellar tendonitis or big toe bursitis. ! 4. A pharmaceutical composition comprising olivic acid or any of its derivatives for the treatment of pathologies involving the activation of COX-2. ! 5. The pharmaceutical composition according to claim 4, containing a pharmaceutically acceptable carrier. ! 6. The composition according to claim 4, containing oleanolic acid. ! 7. The composition according to claim 6, where the ratio between olivic acid and oleanolic acid is from 2: 1 to 6: 1. ! 8. The composition according to claim 4 in a form intended for local administration. ! 9. The composition according to claim 4, where olivic acid or any of its derivatives are obtained from an extract of a plant of the genus Olea. ! 10. The composition according to any one of claims 4 to 9, wherein the olivic acid or any of its derivatives is obtained from a by-product of industrial processing of a plant of the genus Olea. ! 11. The composition according to any one of claims 4 to 9, where the proportion of olivic acid or any of its derivatives is 0.5-3% of the total composition.1. Применение маслиновой кислоты или любого из ее производных в изготовлении лекарственного средства для лечения патологий, включающих активацию циклооксигеназы-2 (COX-2). ! 2. Применение маслиновой кислоты или любого из ее производных в изготовлении лекарственного средства для регенерации хондроцитов в тканях. ! 3. Применение маслиновой кислоты или любого из