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METHODS FOR TREATMENT OF CHRONIC NEUROGENIC INFLAMMATION USING MODIFIED CLOSTRIDIAL TOXIN
专利权人:
Инк. (US);Аллерган
发明人:
ГАКСИОЛА Густаво М. (MX),АГИЛАР Иван Е. (MX),ПАС Гильберто П. (MX)
申请号:
RU2012110324/15
公开号:
RU2012110324A
申请日:
2010.08.10
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
1. A method for treating premature ejaculation in patients in need thereof by means of a clostridial neurotoxin, comprising the step of locally administering clostridial neurotoxin to a patient, followed by treatment of premature ejaculation in a patient. The method according to claim 1, characterized in that the local administration of a therapeutic dose of clostridial neurotoxin is carried out transdermally, intramuscularly, subcutaneously, subdermally, intradermally or implantation, preferably injection. The method according to claim 1, characterized in that the botulinum neurotoxin is selected from the group consisting of type A, B, C, D, E, F and G botulinum neurotoxins, more preferably type A.4 botulinum neurotoxins. The method according to claim 1, characterized in that the clostridial neurotoxin is a botulinum neurotoxin and is administered in an amount of from about 1 unit to 20,000 units. The method according to claim 1, characterized in that the clostridial neurotoxin is a botulinum neurotoxin type A or type B and is administered in an amount of from about 1 unit to 2500 units, or from about 100 to about 10,000 units, respectively. The method according to claim 1, characterized in that the local administration of a therapeutic dose of clostridial neurotoxin to the patient is carried out by injection of clostridial neurotoxin into the patient's penis. The method according to claim 1, characterized in that the clostridial neurotoxin is a botulinum neurotoxin that is administered to a patient member. The method according to claim 7, characterized in that the clostridial neurotoxin is a botulinum neurotoxin type A.9. The method according to claim 7, characterized in that the botulinum1. Способ лечения преждевременной эякуляции у пациентов, нуждающихся в этом, посредством клостридиального нейротоксина, включающий этап локального введения клостридиального нейротоксина пациенту с последующим лечением преждевременной эякуляции у пациента.2. Способ по п.1, отличаю
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