The present invention is directed to inhibitors of tyrosinase, pharmaceutical compositions comprising such tyrosinase inhibitors, and methods of making and using the same. Specifically, included in the present invention are compositions of matter comprised of at least one 2,4-dihydroxybenzene analog, which inhibit the activity of tyrosinase and which inhibit the overproduction of melanin.La présente invention concerne des inhibiteurs de tyrosinase, des compositions pharmaceutiques comprenant de tels inhibiteurs de tyrosinases ainsi que des procédés permettant de les fabriquer et de les utiliser. Plus spécifiquement, la présente invention concerne des compositions dune matière comprenant au moins un analogue de 2,4-dihydroxybenzène, inhibant lactivité de tyrosinase et inhibant la surproduction de mélanine.