PROBLEM TO BE SOLVED: To prevent occurrence of deposition/precipitation when pH of an external preparation containing loxoprofen is lowered by an acid and/or an acidic substance.SOLUTION: Occurrence of deposition/precipitation can be prevented by combining specific surfactants, in details, polyoxyethylene hydrogenated castor oil 40, polyoxyethylene hydrogenated castor oil 50, and polyoxyethylene hydrogenated castor oil 60.