Pharmaceutical composition for the treatment of skin diseases, comprises nitric acid aqueous solution (5-15 mmol/ml), a zinc salt (0.01-0.015 mg zinc ion/ml of the composition) and a copper salt (0.01-0.015 mg copper ion/ml of the composition). Independent claims are included for: (1) a process for the preparation of the composition for the treatment of skin diseases comprising adding zinc metal (0.01-0.015 mg zinc ion/ml) at a predetermined quantity of concentrated nitric acid, stirring the predetermined quantity of nitric acid containing zinc till it dissolves, clearing gaseous hydrogen with a reduction of nitric acid into nitrous acid and forming a first solution, adding a copper, preferably in the form of copper nitrate (0.01-0.015 mg Cu 2> +>ions/ ml), and diluting with water and (2) a medical device comprising an applicator and an ampoule comprising the composition. ACTIVITY : Dermatological Keratolytic Virucide Gynecological Antiinflammatory Antiseborrheic Antipsoriatic Fungicide Antibacterial. MECHANISM OF ACTION : None given.Utilisation, procédé de fabrication dune composition pharmaceutique, composition pharmaceutique pour le traitement de maladies de la peau comprenant une quantité thérapeutique en solution aqueuse dacide nitrique de 5 à 15 mmol/ml de composition pharmaceutique, et comprennent en outre un sel de zinc à une concentration de 0,01 à 0,015 mg ions Zn2+/ml ainsi quun sel de cuivre à une concentration de 0,01 à 0,015 mg ions Cu2+/ml de composition pharmaceutique et son dispositif médical.