ELIZABETH A. HOLMES,SHAUNAK ROY,JOHN HOWARD,CHENGWANG WANG
申请号：
PT04788658
公开号：
PT1662987E
申请日:
2004.09.10
申请国别(地区):
PT
年份:
2012
代理人:
摘要：
The invention relates to an ingestible, implantable or wearable medical device comprising a microarray which comprises a bioactive agent capable of interacting with a disease marker biological analyte； a reservoir which comprises at least one therapeutic agent and is capable of releasing the therapeutic agent(s) from the medical device； and a plurality of microchips comprising a microarray scanning device capable of obtaining physical parameter data of an interaction between the disease marker biological analyte with the bioactive agent； a biometric recognition device capable of comparing the physical parameter data with an analyte interaction profile； optionally a therapeutic agent releasing device capable of controlling release of the therapeutic agent from the reservoirs； an interface device capable of facilitating communications between the microarray scanning device, biometric recognition device and the therapeutic agent releasing device； and an energy source to power the medical device. Specifically, the invention relates to a medical device capable of detecting an analyte in a bodily fluid comprising at least one microneedle capable of obtaining a sample of a bodily fluid, a first microchannel through which the sample flows and is in fluid communication with the at least one microneedle, a second microchannel in fluid communication with the first microchannel, through which a buffer flows, wherein the second channel comprises a microarray with a bioactive agent, a microarray scanning device to detect an interaction between the bioactive agent and the analyte in the bodily fluid； and an interface device.
