crystalline compounds of antiviral sofosbuvir analogues, their use and pharmaceutical composition

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专利权人:

GILEAD PHARMASSET LLC

发明人:

BING SHI,FANG WANG,HYUK-JUN JUNG,KATHLEEN DASHNER,MELISSA JEAN CASTEEL,MUN SIK SEO,VAHID ZIA

申请号：

BR112016013714

公开号：

BR112016013714A2

申请日:

2014.12.08

申请国别(地区):

BR

年份:

2017

代理人:

摘要：

Crystalline solid forms of the anti-HCV compound (S)-isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2- yl)methoxy)(phenoxy)phosphorylamino)propanoate (Compound I) are described Also provided are processes of making and methods of using the crystalline forms.

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中国工程科技知识中心

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http://www.ckcest.cn/home/