Anti-prokineticin receptor (PROKR) antibodies and uses thereof

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专利权人:

Inc.;Regeneron Pharmaceuticals

发明人:

Macdonald, Lynn,Lacroix-Fralish, Michael L..

申请号：

AU2013345018

公开号：

AU2013345018A1

申请日:

2013.11.12

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

The present invention provides antibodies that bind to prokineticin receptors (PROKRs) and methods of using same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to human PROKR1 and/or PROKR2. The present invention includes antibodies that bind cell surface-expressed PROKR1 and/or PROKR2. In certain embodiments, the antibodies of the present invention are capable of blocking prokineticin (PK)- mediated activation of one or more PROKR. The antibodies of the invention are useful for the treatment of various diseases and disorders mediated by prokineticin signaling.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/