The present invention relates to Topical Gel Pharmaceutical product formulation, said preparation contains composition, isolated polypeptide (ACT peptide) of the composition comprising the carboxyl-terminus amino acid sequence with α connection albumen, peptide stabilizer, excipient, buffer etc.. The invention discloses preparations and preparation step that stable, high-quality and drumped topical gel is produced with what. Obtained preparation has the long-time stability for being suitable for beauty and treatment use, including prevention cicatrization and accelerating wound healing.本發明涉及局部凝膠藥物産品製劑,該製劑含有組合物,所述組合物包含具有α連接蛋白的羧基末端氨基酸序列的分離多肽(ACT肽)、肽穩定劑、賦形劑、緩衝劑等。本發明公開了用於生産穩定、優質和可傾倒的局部凝膠的製劑和製備步驟。所得到的製劑具有適用於美容和治療應用的長期穩定性,包括預防瘢痕形成和加速傷口愈合。