WANG JONG-JING,LIN TSUNG-HSIN,HSU CHANG-SHAN,HAO WEI-HUA
申请号：
NZ59665710
公开号：
NZ596657A
申请日:
2010.04.27
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
596657 Disclosed herein is an oral self micro-emulsifying pharmaceutical composition which comprises: A therapeutically effective amount of a hydrophilic drug, preferably bendamustine or gemcitabine, or its pharmaceutically acceptable salt one or more solvents capable of dissolving the hydrophilic drug or its pharmaceutically acceptable salt to form a drug-solvent solution, such as water, glycerol and propylene glycol a surfactant system comprising one or more surfactants such as polysorbate and oleoyl polyoxyglycerides, said surfactant system exhibiting a hydrophilic-lipophilic balance (HLB) value ranging from about 8 to about 17 and one or more hydrophilic carriers, such as polyethylene glycol, which are compatible with said drug-solvent solution and said surfactant system.
