GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人:
JEONG, KWANG WONKR,정광원,SEO, SEUNG YONGKR,서승용
申请号：
KR1020150054598
公开号：
KR1020160124373A
申请日:
2015.04.17
申请国别(地区):
KR
年份:
2016
代理人:
摘要：
The present invention relates to a novel 2-aminoquinolin-8-ol derivative compound which is represented by chemical formula 1. The present invention further relates to a stereoisomer thereof, a pharmaceutically acceptable salt thereof or a solvate thereof, a production method thereof, and a pharmaceutical composition for preventing or treating cancer containing the same as an active ingredient. According to the present invention, the 2-aminoquinolin-8-ol derivative inhibits activities of mixed-lineage leukemia 1 (MLL1), thereby exhibiting outstanding anti-cancer activities.COPYRIGHT KIPO 2016본 발명은 신규 2-아미노퀴놀린-8-올 유도체 화합물, 이의 입체이성질체, 이의 약학적으로 허용 가능한 염, 또는 이의 용매화물, 이의 제조방법, 및 이를 유효성분으로 포함하는 암의 예방 또는 치료용 약학적 조성물에 관한 것이다.
