P. Jeffrey Conn,Craig W. Lindsley,Corey R. Hopkins,Charles David Weaver,Colleen M. Niswender,Darren W. Engers
申请号：
US12952640
公开号：
US08759377B2
申请日:
2010.11.23
申请国别(地区):
US
年份:
2014
代理人:
摘要：
In one aspect, the invention relates to compounds having a general structure:wherein the variables are defined herein, which are useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4) synthetic methods for making the compounds pharmaceutical compositions comprising the compounds and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
