This invention relates to a pharmaceutical composition for treatment of ischemic cerebrovascular disease and senile dementia comprising 1-10 parts by weight of radix ginseng, 1-10 parts by weight of folium ginkgo, 0.05-5 parts by weight of stigma croci and 5-10 parts by weight of glycine max 1. merrill. The components can be the traditional Chinese medicinal materials or the extracts obtained by extracting the same quantity of the Chinese medicinal material. The Chinese medicine composition can be used for the treatment of ischemic cerebrovascular disease and senile dementia.