The present invention provides compositions and methods relating to or derivedfrom anti-PAR-2 antibodies. In particular embodiments, the invention provideshuman antibodies that bind PAR-2, PAR-2-binding fragments and derivativesof such antibodies, and PAR-2-binding polypeptides comprising such fragments.Other embodiments provide nucleic acids encoding such antibodies, antibodyfragments and derivatives and polypeptides, cells comprising such polynucleotides,methods of making such antibodies, antibody fragments and derivatives and polypeptides,and methods of using such antibodies, antibody fragments and derivatives andpolypeptides, including methods of treating or diagnosing subjects havingPAR-2-related disorders or conditions.
