THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
发明人:
THOMAS, PHILIP J.,SIEGWART, DANIEL J.,JOHNSON, ARTHUR E.,TORRES, MICHAEL J.,MILLER, JASON B.
申请号：
CA3024135
公开号：
CA3024135A1
申请日:
2017.05.16
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
In some aspects, the present disclosure provides a nanoparticle composition comprising tRNA and an aminolipid delivery compound. The aminolipid delivery compound may be a dendrimer, dendron, or dendritic lipid, a polymer such as a polyamide or polyester, or a lipid with one or more hydrophobic components. In some embodiments, these compositions may be administered to a patient to treat a genetic disease or disorder such as cystic fibrosis, Duchene muscular dystrophy, or cancer.
