PROBLEM TO BE SOLVED: To provide a method of inhibiting fat differentiation and a pharmaceutical composition that inhibits fat differentiation.SOLUTION: This invention provides a fat differentiation inhibitor that comprises a peptide D composed of an amino acid sequence represented by the sequence number 1 as an active ingredient, and a pharmaceutical composition for prevention or treatment of fat metabolism disease, comprising the fat differentiation inhibitor.COPYRIGHT: (C)2015,JPO&INPIT【課題】脂肪分化を抑制する方法及び脂肪分化を抑制する医薬組成物の提供。【解決手段】配列番号1に表されるアミノ酸配列からなるペプチドDを有効成分として含む、脂肪分化抑制剤、及び該脂肪分化抑制剤を含む脂肪代謝疾患の予防又は治療用医薬組成物。【選択図】なし