The General Hospital Corporation;Chugai Seiyaku Kabushiki Kaisha
发明人:
申请号：
EP11781266.9
公开号：
EP2569003B1
申请日:
2011.05.12
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
Disclosed are two PTH analog ligands, SP-PTH-AAK and Aib-SP-PTH-AAK, that have long-acting activity at the PTH receptor, as demonstrated both in vitro and in vivo. These polypeptides are thus particularly useful in the treatment of diseases, such as hypoparathyroidism, in which long-acting activity is desired. The method of making the analog polypeptides is also disclosed.
