INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY;경상대학교산학협력단
发明人:
YOON, SUNG CHUL,윤성철,CHOI, MUN HWAN,최문환,MOHSIN SHAH,모흐신 사
申请号：
KR1020110128466
公开号：
KR1020130062058A
申请日:
2011.12.02
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A drug delivery formulation which is able to improve supporting ability of a hydrophobic drug, and a method for drug delivery using the same are provided to increase supporting ability and to be effectively used as a drug delivery formulation. CONSTITUTION: A target-specific drug delivery formulation contains a drug which is loaded in an amorphous P(3-hydroxyvalerate-co-4hydroxyburylate)-b-monomethoxy polyethylene glycol(p(3HV-co-4HB)-b-mPEG) copolymer. The drug is a hydrophobic drug, cisplatin. A target-specific drug delivery method comprises a step of loading the drug in amorphous p(3HV-co-4HB)-b-mPEG copolymer.본 발명은 무정형의 poly(3-hydroxyvalerate-co-4-hydroxybutyrate)(P(3HV-co-4HB))-b-monomethoxy polyethylene glycol(mPEG) 공중합체에 약물이 적재된 것을 특징으로 하는 타깃 특이적 약물 전달 제재 및 이를 이용한 타깃 특이적 약물 전달 방법에 관한 것이다. 보다 구체적으로 본 발명은 소수성 약물의 담지력을 향상시킬 수 있는 약물 전달 제재 및 이를 이용한 약물 전달 방법에 관한 것이다.
