Shanghai Hengrui Pharmaceutical Co., Ltd.;Jiangsu Hengrui Medicine Co., Ltd.
发明人:
Zhuoxiao Cao,Yayuan Fu,Qiyue Hu,Weikang Tao,Lianshan Zhang,Piaoyang Sun
申请号：
US16312174
公开号：
US20190233513A1
申请日:
2017.06.22
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Provided are a LAG-3 antibody, an antigen-binding fragment thereof, and a pharmaceutical application thereof. Further, provided are a chimeric antibody comprising a CDR of the LAG-3 antibody, a humanized antibody, a pharmaceutical composition comprising the LAG-3 antibody and the antigen-binding fragment thereof, and an application of the pharmaceutical composition as an antineoplastic drug. Particularly, provided is an application of a humanized LAG-3 antibody in preparation of drugs for treatment of diseases involving immune cells.
