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New 5-aminotetrahydroquinolin-2-carboxylic acids and their use
专利权人:
Bayer Pharma Aktiengesellschaft
发明人:
HAHN, Michael,FOLLMANN, Markus,HÜBSCH, Walter,BECKER-PELSTER, Eva-Maria,STASCH, Johannes-Peter,KELDENICH, Joerg,DELBECK, Martina,TINEL, Hanna,WUNDER, Frank,MITTENDORF, Joachim,TEREBESI, Ildiko,LANG, D
申请号:
ES13744464
公开号:
ES2616036T3
申请日:
2013.07.16
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
Compound of the formula (I) ** Formula ** in which R1 represents hydrogen or fluorine, L1 represents ethan-1,2-diyl or 1,4-phenylene, and A represents a group of the formula ** Formula ** where * indicates the respective point of attachment to the rest of the molecule, L3 means a bond, -O-, -CH2-, -CH2-CH2- or -CH>; = CH-, and R3C means a substituent selected from the group of fluorine, chlorine, bromine, cyano, (C1-C4) alkyl, difluoromethyl, trifluoromethyl, (C1-C4) alkoxy, difluoromethoxy and trifluoromethoxy, and R3D means a substituent selected from the group of hydrogen, fluorine, chlorine, bromine, cyano, (C1-C4) alkyl, difluoromethyl, trifluoromethyl, (C1-C4) alkoxy, difluoromethoxy and trifluoromethoxy, as well as their salts, solvates and solvates of the salts.Compuesto de la fórmula (I) **Fórmula** en el que R1 representa hidrógeno o flúor, L1 representa etan-1,2-diilo o 1,4-fenileno, y A representa un grupo de la fórmula**Fórmula** en la que * indica el punto de enlace respectivo al resto de la molécula, L3 significa un enlace, -O-, -CH2-, -CH2-CH2- o -CH>;=CH-, y R3C significa un sustituyente seleccionado del grupo de flúor, cloro, bromo, ciano, alquilo (C1-C4), difluorometilo, trifluorometilo, alcoxi (C1-C4), difluorometoxi y trifluorometoxi, y R3D significa un sustituyente seleccionado del grupo de hidrógeno, flúor, cloro, bromo, ciano, alquilo (C1-C4), difluorometilo, trifluorometilo, alcoxi (C1-C4), difluorometoxi y trifluorometoxi, así como sus sales, solvatos y solvatos de las sales.
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