Improved anti-TNFR1 polypeptides, antibody variable domains & antagonists

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专利权人:

GLAXO GROUP LIMITED

发明人:

DUFFIELD, STEPHEN,ENEVER, CAROLYN,LIU, HAIQUN,SCHON, OLIVER,SEPP, ARMIN,STOOP, ALLART ADRIAAN

申请号：

AU2010215479

公开号：

AU2010215479B2

申请日:

2010.02.17

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

The invention relates to anti-TNFR1 polypeptides, antibody single variable domains (dAbs), antagonists and multispecific ligands, as well as methods and uses of these. The anti-TNFR1 polypeptides, antibody single variable domains (dAbs), antagonists and multispecific ligands are useful for treating and/or preventing inflammatory disease, such as arthritis or COPD, as well as for pulmonary administration, oral administration, delivery to the lung and delivery to the GI tract of a patient.

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