To provide a novel JAK3 inhibitor that is useful asa preventive and/or therapeutic agent for rejection andgraft versus host disease (GvHD) in organtransplantation, rheumatoid arthritis, multiplesclerosis, systemic lupus erythematosus, Sjögrensyndrome, Behcet's disease, type I diabetes mellitus,autoimmune thyroiditis, idiopathic thrombocytopenicpurpura, ulcerative colitis, Crohn's disease, asthma,allergic rhinitis, atopic dermatitis, contact dermatitis,urticaria, eczema, psoriasis, allergic conjunctivitis,uveitis, cancer, leukemia and the like. The pyridine-3-carboxyamidederivative represented by the generalformula (1):(see general formula 1)or its salt or a solvate thereof.
