The present invention relates to improving the solubility of drospirenone by providing the drospirenone as an inclusion complex formed between cyclodextrin and drospirenone. In a specific embodiment of the invention, the cyclodextrin is beta -cyclodextrin. The invention further relates to methods of providing such an inclusion complex, and to the use of said inclusion complex in pharmaceutical compositions for use as a medicament in the treatment of symptoms associated with menopause and in female contraception.