WANG, YI,MCKNIGHT, SUSAN FAAS,YU, ZHAO-XUE,WANG, HAO
申请号：
TW101103494
公开号：
TW201244737A
申请日:
2012.02.03
申请国别(地区):
TW
年份:
2012
代理人:
摘要：
The present disclosure provides methods useful for prolonging the survival of an allograft organ in a recipient mammal. The methods include administration of an anti-CD200 antibody or a CD200-binding fragment of the antibody. The disclosure also provides biomarkers, a change in one or more of which indicates that an anti-CD200 antibody has produced a desired immunomodulatory effect in a mammal. Also featured are pharmaceutical compositions, kits, and solutions that contain at least one anti-CD200 antibody and are useful in the methods described herein.
