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Methods for Identifying Compounds that Directly Bind to Insect Transient Receptor Potential Channels
专利权人:
BASF SE
发明人:
Alexandre Nesterov,Ramani Kandasamy,Wolfgang von Deyn,Damian London,Katherine Lelito,Vincent L Salgado
申请号:
US15737170
公开号:
US20180220653A1
申请日:
2016.06.17
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to a screening method for determining whether or not a candidate compound directly binds to an insect transient receptor potential V (TRPV) channel. The present invention further provides a method of identifying a compound that directly binds to a Nanchung protein, TRP and/or TRPV protein and/or channel using, a binding assay. The present invention further provides a method of classifying an insecticide compound by its mode of action using the binding assay and/or a functional assays.
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