ASHWELL, Susan,CAMPBELL, Ann-Marie,CARAVELLA, Justin Andrew,DIEBOLD, R. Bruce,ERICSSON, Anna,GUSTAFSON, Gary,LANCIA, David R. Jr.,LIN, Jian,LU, Wei,WANG, Zhongguo
申请号:
LT18198969
公开号:
LT3447050T
申请日:
2015.09.18
申请国别(地区):
LT
年份:
2020
代理人:
摘要:
The invention relates to inhibitors of mutant isocitrate dehydrogenase (mt-IDH) proteins with neomorphic activity useful in the treatment of cell-proliferation disorders and cancers, having the Formula: (I) where A, U, W1, W2, W3, R1-R6, and R9 are described herein.