#$%^&*AU2013257410A120131128.pdf#####H:\rbr\Intrwoven\NRPortbl\DCC\RBR\5805916_I.DOC-I 1/11/2013 ABSTRACT The invention relates to the use of a pyrimidylaminobenzamides of formula (1) wherein the radicals have the meanings as defined herein, or of a pharmaceutically acceptable salt thereof for the manufacture of pharmaceutical compositions for use in the treatment of fibrosis, to the use of a pyrimidylaminobenzamides of formula (1) or pharmaceutically acceptable salt thereof in the treatment of fibrosis, to a method of treating warm-blooded animals including humans suffering from fibrosis by administering to a said animal in need of such treatment an effective dose of a pyrimidylaminobenzamide of formula I or a pharmaceutically acceptable salt thereof, and to combinations comprising (a) at least one pyrimidylaminobenzamides of formula (1) as and (b) at least one compound selected form AT1 -receptor antagonists and ACE inhibitors and the use of such combinations in the treatment of fibrosis, in particular hepatic fibrosis. N Py N NH R4 R2 (0)
