Anders Falk Vikbjerg;Mogens Winkel Madsen;Sune Allan Petersen
发明人:
Mogens Winkel Madsen,Sune Allan Petersen,Anders Falk Vikbjerg
申请号：
US13503614
公开号：
US09820941B2
申请日:
2010.10.25
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention provides a composition comprising a sPLA2 hydrolysable liposome, an exterior solution, and an interior solution within the liposome, —wherein the concentration of osmolytes is higher in the interior solution than in the exterior solution. The composition improves storage stability of sPLA2 hydrolysable liposomes, in particular at when stored at 2-8 degrees Celsius. The liposome preferably encapsulates cisplatin. The invention also provides methods of preparing the composition of the invention.
