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Topical composition comprising a film-forming polymer for delivering an active ingredient to skin
专利权人:
LEO PHARMA A/S
发明人:
Karsten Petersson,Kit Frederiksen,Diana Omkvist,Jörgen Jansson
申请号:
US14412978
公开号:
US09345774B2
申请日:
2013.07.05
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A sprayable film-forming pharmaceutical composition for dermal application comprises at least one therapeutically active ingredient dissolved in a pharmaceutically acceptable propellant selected from the group consisting of dimethyl ether, diethyl ether and methylethylether, and a mixture of dimethyl ether, diethylether and methylethyl ether, and a second propellant selected from C3-5 alkanes, hydrofluoroalkanes, hydrochloroalkanes, fluoroalkanes and chlorofluoroalkanes, the propellant being present in an amount of 50-99.5% w/w of the composition, the composition further comprising a film-forming polymer, a plasticizer and an oily release-enhancing agent.
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